论文部分内容阅读
老年人高尿酸血症和肾脏的关系甚密切。本组血尿酸(SUA)男性为481.8μmol/L;女性为459.2 μmol/L。老年人高尿酸血症的发生,主要系由肾脏排泄尿酸的功能减退所致,而且多伴发肾小管功能减退,表现为远端肾小管功能受损,浓缩功能减退,以及近端肾小管功能被累及,使尿尿酸排泄减少与β_2微球蛋白(β_2-MG)重吸收不全。近端肾小管功能不全的早期发现以检测尿β_2-MG较尿溶菌酶为敏感。高尿酸血症多伴发高甘油三酯血症,两者呈显著正相关。
The relationship between hyperuricemia and kidney in the elderly is very close. This group of uric acid (SUA) male 481.8μmol / L; female 459.2 μmol / L. The incidence of hyperuricemia in the elderly is mainly due to the excretion of uric acid by the kidneys due to hypofunction, and more associated with renal tubular dysfunction, manifested as distal tubular dysfunction, concentration dysfunction, and proximal tubular function Was involved, so that decreased uric acid excretion and β 2 microglobulin (β_2-MG) reabsorption. Early detection of proximal tubular insufficiency was more sensitive than urinary lysozyme in detecting urinary β_2-MG. Hyperuricemia associated with hypertriglyceridemia, a significant positive correlation between the two.