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目的探讨氧气驱动雾化吸入方式对小儿支气管哮喘患儿血管紧张素系统及气道重塑的影响。方法将2011年12月~2013年2月于本院进行治疗的74例小儿支气管哮喘患儿随机分为(超声雾化吸入组)37例和观察组(氧气驱动雾化吸入组)37例,然后将两组患儿治疗前后的血浆血管紧张素及气道重塑相关指标进行比较。结果观察组的治疗后血浆血管紧张素及其受体及气道重塑相关指标均明显优于对照组,P均<0.05。结论氧气驱动雾化吸入方式对小儿支气管哮喘患儿血管紧张素系统及气道重塑的影响较大。
Objective To investigate the effects of aerosol-driven inhalation on angiotensin system and airway remodeling in children with bronchial asthma. Methods A total of 74 children with bronchial asthma treated in our hospital from December 2011 to February 2013 were randomly divided into two groups: 37 cases in the group receiving ultrasonic inhalation and 37 cases in the observation group receiving aerosol inhalation. Then two groups of children before and after treatment of plasma angiotensin and airway remodeling related indicators were compared. Results After treatment, the observed values of plasma angiotensin, its receptor and airway remodeling in the observation group were significantly better than those in the control group (all P <0.05). Conclusion Oxygen-driven atomization inhalation has a significant effect on angiotensin system and airway remodeling in children with bronchial asthma.