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急性粒细胞单核细胞性白血病(以下简称粒单细胞性白血病)与急性粒细胞性白血病的区别在于前者的原始细胞可与包被抗Rh抗体的人Rh(D)阳性红细胞形成花环。根据这特点,似乎粒单细胞性白血病的原始细胞有Fc受体,而原粒细胞无Fc受体。由于包被兔抗羊红细胞抗体的羊红细胞可与成熟粒细胞形成花环,显然,正常粒细胞是有Fc受体的。白血病的原粒细胞不能和人抗体形成花环的一个原因,可能是与结合到指示红细胞的Ig的密度有关。与此有关的事实是,只有用超免疫的抗CD(Ripley)血清致敏的Rh阳性红细胞才能与人粒细胞发生花环形成。作者想知道不能查出原粒细胞上的Fc受体的
Acute myelomonocytic leukemia (hereinafter referred to as “myelomonocytic leukemia”) differs from acute myelogenous leukemia in that the former primordial cells form a rosette with human Rh (D) -positive erythrocytes coated with anti-Rh antibody. According to this trait, it appears that the primordial cells of granulocytic leukemia have Fc receptors, whereas the myeloblasts have no Fc receptors. Since sheep red blood cells coated with rabbit anti-sheep red blood cells can form a rosette with mature granulocytes, obviously, normal granulocytes have Fc receptors. One reason that leukemia-derived myeloblasts can not form rosette with human antibodies may be related to the density of Ig binding to erythrocytes. In connection with this fact, only Rh-positive erythrocytes that is sensitized with hyperimmune anti-CD (Ripley) serum can form a rosette with human granulocytes. The authors wonder if they can not detect Fc receptors on their neutrophils