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七十年代以来,国内外报道应用HBsAg健康携带者的血液,经纯化留下直径为22nm小球形颗粒(即HBsAg),用甲醛灭活制成乙型肝炎疫苗接种,以预防乙型肝炎。按VIO专家小组建议,在疫苗制成后宜用对(?)肝炎病毒(HBV)敏感的灵长类动物作试(?)。据报道某些灵长类如狨猴(marmoset)亦能接受感染,而恒河猴之类则难以感染。最适宜的动物为黑猩猩(chimpanzee)。以后发现长臂猿(gibbon)也有类似的敏感性。猩猩来源困难。我国云南、海南岛等地有长臂猿,但捕获的很少。本文报告白掌长臂猿(Hrlobates lar
Since the seventies, the blood of HBsAg healthy carriers has been reported at home and abroad. After purification, small spherical particles (ie, HBsAg) with a diameter of 22 nm are left behind, and hepatitis B vaccination is inactivated by formaldehyde to prevent hepatitis B infection. As recommended by the VIO expert group, primates susceptible to (?) Hepatitis virus (HBV) should be tested (?) After the vaccine is prepared. Some primates, such as the marmoset, have also been reported to be infected, while rhesus macaques and the like have been found to be difficult to infect. The most suitable animal is chimpanzee. Later gibbons were found to have similar sensitivities. Orangutan origin is difficult. China’s Yunnan, Hainan Island and other places gibbons, but seldom captured. This article reports white-handed gibbons (Hrlobates lar