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目的观察中药制剂抗震止痉胶囊联合还原型谷胱甘肽治疗帕金森病(肝肾不足、虚风内动证)患者的疗效。方法将85例患者随机分为两组。观察组予西医常规治疗且口服抗震止痉胶囊、静滴还原型谷胱甘肽,对照组仅接受西医常规治疗,3周为1疗程;治疗前后分别进行Hoehn-Yahr分级及帕金森病统一评分量表第2分量表(UPDRSⅡ)评分,以评定临床疗效,同时根据病情变化适当调整基础治疗药物并进行比较。结果治疗组Hoehn-Yahr分级及UPDRSⅡ评分的改善均优于对照组。结论在西医常规治疗基础上加用抗震止痉胶囊、还原型谷胱甘肽治疗帕金森病的临床疗效优于单独使用西医常规治疗。
Objective To observe the curative effect of the Chinese medicine preparation Kang Se Zijing Capsule combined with reduced glutathione in the treatment of Parkinson’s disease (liver and kidney insufficiency, virtual wind dynamic card). Methods 85 patients were randomly divided into two groups. The observation group was treated with routine western medicine and oral anti-Seizhentang capsule and intravenous reduction glutathione. The control group received conventional western medicine only for 1 week. The Hoehn-Yahr grade and Parkinson’s disease score Scale Table 2 (UPDRS Ⅱ) score, to assess the clinical efficacy, and based on changes in the condition of the appropriate adjustments to the basic treatment drugs and compared. Results The improvement of Hoehn-Yahr grade and UPDRSⅡ grade in treatment group were better than that of control group. Conclusion The clinical curative effect of retrograde GSK on Parkinson’s disease is better than that of Western medicine alone.