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纳洛酮(naloxone,NLX)为竞争性、特异性阿片受体拮抗剂,其与分布在脑干等部位的阿片受体结合后,能有效地阻断内啡肽(EP)、强啡肽和脑啡肽等内源性阿片样物质所介导的镇痛、抑制呼吸、降低血压、减慢心率、促进生长激素和促甲状腺素释放,升高血糖,促进缺血性脑水肿的形成和发展
Naloxone (NLX), a competitive and specific opioid receptor antagonist, binds to opioid receptors distributed in the brainstem and other parts of the body and effectively blocks endorphin (EP), dynorphin And enkephalin and other endogenous opioid-mediated analgesia, inhibition of respiration, lower blood pressure, heart rate, promote the release of growth hormone and thyrotropin, increase blood sugar, promote the formation of ischemic brain edema and development of