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使用两种浓度乙酸经皮局部注射治疗小鼠肝癌(H22)。分别采用15%、30%浓度的乙酸进行瘤内注射硬化治疗,发现30%浓度组效果更好,各浓度组均未发现对动物体的明显毒副作用,与无水乙醇治疗组相比无显著差异。提示在经皮局部注射治疗肝癌时,对无水乙醇不适合的患者,可采用30%乙酸
Mouse liver cancer (H22) was treated with two concentrations of acetic acid transdermally. Respectively, with 15%, 30% acetic acid for intratumoral injection sclerosis treatment and found that the 30% concentration group effect is better, each concentration group were found no significant side effects on animals, compared with the anhydrous ethanol treatment group was not significant difference. Prompt transdermal local injection in the treatment of liver cancer, anhydrous ethanol is not suitable for patients, can use 30% acetic acid