Synthesis,Crystal Structure and URAT1 Inhibitory Activity of 2-（（5-Bromo-4-（（4-cyclobutylnaphth-1-yl

来源 :结构化学 | 被引量 : 0次 | 上传用户：lz251667032

【摘要】

：

The title compound 1 was prepared from 1-bromonaphthalene and cyclobutanone in 11 steps, and its structure was determined by single-crystal X-ray diffraction fo

【作者】

：

ZHANG Xian-Sheng XIN Xiao LIU

【机构】

：

SchoolofChemistryandChemicalEngineering,TIanjinKeyLaboratoryofMolecularDesignandDrugDiscovery,Shando

【出处】

：

结构化学

【发表日期】

：

2017年9期

【关键词】

：

抑制活性晶体结构单晶X-射线衍射分子间氢键合成乙酸硫基 1-溴代萘 synthesis crystal structure URAT1 inhi

【基金项目】

：

Supported by the Key Projects of Tianjin Science and Technology Support Plan（16YFZCSY00910）, Tianjin Natural Science Foundation（12JCYBJC18800 and 13JCQNJC13700）, Shandong Natural Science Foundation（ZR

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论文部分内容阅读

The title compound 1 was prepared from 1-bromonaphthalene and cyclobutanone in 11 steps, and its structure was determined by single-crystal X-ray diffraction for its monohydrate. The title compound 1 crystallizes as its monohydrate(C_(19)H_(18)BrN_3O_2S&#

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Synthesis,Crystal Structure and URAT1 Inhibitory Activity of 2-（（5-Bromo-4-（（4-cyclobutylnaphth-1-yl

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