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众所周知,皮肤黑素瘤是一种高度恶性的肿瘤,多数人认为采用原发灶和引流区淋巴结广泛切除术是治疗皮肤黑素瘤的合适方法,而对采用术前放射治疗的问题尚有争论。本文报道82例皮肤黑素瘤病例,对其中36例原发性恶性黑素瘤的治疗结果作了重点分析,其中女性22例,男性14例,女性患者的病变多数发生在四肢皮肤(45%),而男性患者以躯干皮肤多见(23.5%),年龄主要为30～50岁。按国际TNM分期,ⅠⅡ期病人占86.1%。大多数病人没有区域淋巴结肿大。从手术切除标本按(?)标准进行肿瘤侵袭真皮程度的分级:Ⅰ级为2例,Ⅱ级9例,Ⅲ级11例,Ⅳ级10例,Ⅴ级4例。
It is well known that cutaneous melanoma is a highly malignant tumor. Most people believe that the use of extensive resection of primary and draining lymph nodes is a suitable method for the treatment of cutaneous melanoma. The use of preoperative radiation therapy remains controversial. . This article reported 82 cases of cutaneous melanoma, and analyzed the results of treatment of 36 cases of primary malignant melanoma, including 22 cases of females and 14 cases of males. Most of the lesions of female patients occurred in the skin of the extremities (45%). ), while male patients are more common with the trunk skin (23.5%), mainly for the age of 30 to 50 years old. According to the international TNM stage, patients with stage III accounted for 86.1%. Most patients do not have regional lymphadenopathy. The grades of tumor invasion from the surgical specimens according to (?) criteria were grade II: 2 cases, grade II 9 cases, grade III 11 cases, grade IV 10 cases, and grade V 4 cases.