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近年来,国内外学者将核仁形成区嗜银蛋白(AgNORs)银染技术应用于肿瘤病理诊断和研究,但以往对恶性肿瘤分型、分级的研究,因限于单项计数指标,且标本数少,所以结果不尽一致。本研究除从AgNORs数量外,并在形态、大小和分布等定量指标对结肠癌进行统计分析,以探讨该技术对结肠癌分型、分级的诊断意义。 材料和方法 114例结肠癌为该院病理科1984～1991年结肠癌住院病人手术切除存档病理蜡块标本。组织学分类为:管状腺癌86例(包括高分化29
In recent years, domestic and foreign scholars have applied AgNORs silver staining technology to tumor pathological diagnosis and research. However, in the past, studies on the classification and grading of malignant tumors were limited to single counts and the number of specimens was small. , so the results are not consistent. In this study, in addition to the number of AgNORs, statistical analysis was performed on the quantitative indicators such as morphology, size, and distribution to explore the diagnostic significance of this technique for the classification and grading of colon cancer. Materials and Methods 114 cases of colon cancer were histological specimens of paraffin-embedded specimens of colon cancer patients hospitalized in the Department of Pathology from 1984 to 1991. Histological classification: 86 cases of tubular adenocarcinoma (including highly differentiated 29