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目的探讨小儿毛细血管渗漏综合征的临床特点、治疗措施。方法回顾性分析我院NICU2009年6月至2012年6月收治的11例CLS患儿的临床表现、治疗措施及转归。结果 11例患儿中,原发病为先心病5例,脓毒症6例;均出现进行性皮肤黏膜水肿、呼吸困难、不同程度休克、尿少、低白蛋白血症。结论 CLS是小儿重症感染的严重并发症,病死率高,早期在综合治疗基础上给予羟乙基淀粉,恢复期应用速尿可提高抢救成功率。
Objective To investigate the clinical features and treatment of pediatric capillary leak syndrome. Methods The clinical manifestations, treatment and outcomes of 11 CLS children admitted to our NICU from June 2009 to June 2012 were retrospectively analyzed. Results Among the 11 children, the primary disease was 5 cases of congenital heart disease and 6 cases of sepsis. All patients had progressive cutaneous mucosal edema, dyspnea, shock of different degrees, oliguria and hypoalbuminemia. Conclusion CLS is a serious complication of severe infection in children with high mortality rate, early treatment of hydroxyethyl starch based on comprehensive treatment, furosemide during recovery can improve the success rate of rescue.