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目的:探讨糖尿病非酮症高渗综合征(DNHS)的诊断及治疗。方法:回顾性分析我院2007年9月～2010年9月住院治疗的21例DNHS患者的临床资料,分析其诱因、临床表现、实验室检查及治疗情况。结果:21例DNHS患者中年龄>60岁12例,12例为2型糖尿病,9例发病前无糖尿病;诱因主要是感染、心脑血管意外等,入院后72小时内病死率高于72小时后病死率。结论:早期给予有效补液、正确使用胰岛素、纠正电解质紊乱、积极预防并发症可降低DNHS患者病死率。
Objective: To investigate the diagnosis and treatment of diabetic nonketotic hypertonic syndrome (DNHS). Methods: The clinical data of 21 DNHS patients hospitalized from September 2007 to September 2010 in our hospital were retrospectively analyzed. The causes, clinical manifestations, laboratory tests and treatment were analyzed. Results: Among 21 DNHS patients, 12 were aged> 60 years, 12 were type 2 diabetes and 9 were non-diabetic before onset. The predisposing factors were mainly infection, cardiovascular and cerebrovascular accidents. The mortality rate was higher than 72 hours after admission After the case fatality rate. CONCLUSION: Effective early rehydration, proper use of insulin, correct electrolyte imbalance, and active prevention of complications may reduce the mortality of DNHS patients.