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目的初步探讨婴幼儿特发性血小板减少性紫癜 (ITP)的病因 ,分析其疗效。方法对 135例 0～ 3岁ITP进行临床分析。结果 135例中 90例发生于病毒感染性疾病之后 ,占 6 6 .7% ;15例发生于疫苗注射后 ,占 11.1% ;5例发生于支原体感染之后 ,占 3.7% ;5例弓形虫IgM阳性 ,占 3.7% ;2 0例原因不明 ,占 14.8% ,发生ITP。其中急性118例 ,占 87.4% ;慢性 17例 ,占 12 .6 %。结论 :病毒与血小板减少性紫癜发病有关 ,0～ 1岁ITP患儿疗效较 1～ 3岁ITP患儿好 ,血小板相关抗体IgG(PAIgG)的高低及变化可以作为判断疗效和预后的一个指标。
Objective To investigate the etiology of idiopathic thrombocytopenic purpura (ITP) in infants and young children and analyze its curative effect. Methods The clinical data of 135 ITP patients aged 0-3 years were analyzed. Results Of 135 cases, 90 cases occurred after viral infection, accounting for 6.67%; 15 cases occurred after vaccine injection, accounting for 11.1%; 5 cases occurred after mycoplasma infection, accounting for 3.7%; 5 cases of Toxoplasma gondii IgM Positive, accounting for 3.7%; 20 cases of unknown cause, accounting for 14.8%, ITP occurred. Among them, 118 cases were acute, accounting for 87.4%; 17 cases were chronic, accounting for 12.6%. Conclusions: The incidence of thrombocytopenic purpura is related to the incidence of thrombocytopenic purpura. The efficacy of ITP children aged 0-1 years old is better than that of ITP children aged 1-3 years. The level of platelet-associated antibody IgG (PAIgG) may be used as an index to judge the curative effect and prognosis.