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【答】急性风湿热继发于A簇乙型溶血性链球菌感染已为多数学者承认。其发病机理可能为:(1)机体对链球菌细胞或细胞外物质的直接反应;(2)链球菌刺激机体的免疫过程,发生过敏反应;(3)链球菌或其变异型的持续感染。风湿热复发者有95%的血清抗透明质酸酶、抗链球菌激酶和抗链球菌溶血素“O”均显著升高。所以,教科书上及国内外学者均认为风湿热复发与链球菌感染有肯定关系。劳累和寒冷易导致链球菌性上呼吸道感染,促使风心病者发生心脏代偿机能不全,使病情加重。
[A] acute rheumatic fever secondary to A cluster B hemolytic streptococcal infection has been recognized by most scholars. Its pathogenesis may be: (1) the body’s direct response to Streptococcus cells or extracellular substances; (2) streptococcus stimulate the body’s immune process, anaphylactic reactions; (3) streptococci or variants of persistent infection. Rheumatic fever relapse 95% of the serum anti-hyaluronidase, anti-streptokinase and anti-streptolysin “O ” were significantly higher. Therefore, textbooks and scholars at home and abroad are that rheumatic fever relapse and streptococcal infection have a positive relationship. Tired and cold easily lead to streptococcal upper respiratory tract infection, promote heart failure occurs in patients with rheumatic heart failure compensatory function, so that the disease worsened.