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克山病是全身性疾病,但以心脏病变为最显著。心脏的病变主要为心肌之溶解、崩解及瘢痕形成。尤以肉柱及心肌内层更为显著。其中有部分病例发生广泛的心内膜下心肌急性坏死,临床上构成了所谓急性心内膜下心肌坏死型。克山病心肌坏死在临床上与急性心肌梗死相似,如表现为休克或心脏性哮喘等。但无持续性心前区疼痛,因此临床上容易忽略,尤其对于急性心内膜下心肌坏死,临床上往往估计不到。
Keshan disease is a systemic disease, but heart disease is the most significant. Cardiac lesions mainly for myocardial dissolution, disintegration and scarring. Especially in the meat column and the myocardium is more significant. In some cases, there is a wide range of acute myocardial endocardial necrosis, the clinical form of the so-called acute subendocardial myocardial necrosis. Keshan disease myocardial necrosis in clinical and acute myocardial infarction similar, such as the performance of shock or cardiac asthma. But no persistent pre anterior area pain, it is easy to ignore clinically, especially for acute subendocardial myocardial necrosis, clinically often underestimated.