自Chu(1965)及Saffiotti(1967)分别报告维生素甲类化合物可阻断多环烃引起前胃癌、宫颈癌,以及苯并芘诱发的肺癌以来,这类化合物在肿瘤防治上的潜力已引起广泛注意。一、维生素甲类化合物的化学结构与生物活性。远在1929年Euler等及Moore同时报告胡萝卜素是维生素甲的重要来源,在植物中广泛存在,其化学结构如下。 Since Chu (1965) and Saffiotti (1967) reported that vitamin A compounds can block polycyclic hydrocarbon-induced pre-cancer, cervical cancer, and benzphetone-induced lung cancer, the potential of this class of compounds for cancer control has been extensive. note. First, the chemical structure and biological activity of vitamin A compounds. As far back as 1929, Euler et al. and Moore also reported that carotene is an important source of vitamin A. It is widely found in plants and its chemical structure is as follows.