PGs在生殖中的作用早为人们重视,而PGs与雄性生殖的关系又是一个相当有发展前途的领域。我们曾报道了棉酚对大鼠血浆PGs的影响,最近又报道了棉酚对大鼠睾丸间质细胞腺苷酸环化酶活性、环核苷酸、PGs及睾丸酮含量的影响。为进一步探讨棉酚在体内的抗生育作用原理,本文观察了醋酸棉酚对雄性大鼠生殖器官(睾丸、附睾、输精管、精囊)PGs含量的影响。 The role of PGs in reproduction has long been valued by people, and the relationship between PGs and male reproduction is another promising field. We reported on the effects of gossypol on plasma PGs in rats and recently reported the effects of gossypol on adenylate cyclase activity, cyclic nucleotide, PGs and testosterone levels in rat leydig cells. In order to further explore the anti-fertility mechanism of gossypol in vivo, we investigated the effect of gossypol acetate on the PGs content of reproductive organs (testis, epididymis, vas deferens and seminal vesicles) in male rats.