从1973年起,我组着手开始建立周期型马来丝虫的小动物模型。在实验工作中,选择对马米丝虫感染率高,饲养又方便的蚊种是一个重要的课题。中华按蚊为我国马来丝虫的重要自然媒介之一,国内曾报道用周期型马来丝虫以中华按蚊作媒介感染猫、猴获得成功。近年来上海昆虫研究所又成功地实验室饲养并驯化了该蚊种。因此,自1974年6月至1975年5月我们重点以驯化的中华按蚊为媒介进行了人工感染周期型马来丝虫试验,并将感染后获得的感染蚴接种于长爪沙鼠与猕猴体内,以后进行 Since 1973, our group has started to set up a small animal model of periodic malayian worm. In the experimental work, it is an important issue to choose the mosquito species which has high infection rate and breeding and convenient to Mami filariasis. Anopheles sinensis is one of the most important natural vectors of Malayan filariasis in China. It has been reported that mosquitoes infected with mosquitoes of the genus Anopheles sinensis are infected with periodic malayian filariasis. In recent years, the Shanghai Insect Institute has succeeded in breeding and domestication of the mosquito species in the laboratory. Therefore, from June 1974 to May 1975, we focused on the domesticated An. Sinensis mosquitoes as a medium for the artificial infection of periodic Malayan worm test, and infected infected larvae were inoculated in gerbils and macaques In vivo, later