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目的探讨老年人社区获得性肺炎序贯疗法的临床疗效,并进行成本分析。方法将2009年1月至2011年12月我科住院确诊的老年社区获得性肺炎患者69例,随机分为两组:对照组给予头孢曲松钠针3.0加生理盐水100 ml、阿奇霉素针0.5加5%GS250 ml静脉滴注,1次/d;序贯治疗组先以相同的方法和药物治疗3～4 d,待病情明显改善后,改为口服头孢克肟片0.1 g,2次/d,阿奇霉素片0.51次/d,总疗程均为10 d。观察两组疗效、计算成本,并进行比较。结果两组临床疗效均较好,比较差异无统计学意义(P>0.05),但序贯治疗组的费用低,两组比较差异有统计学意义(P<0.05)。结论住院老年社区获得性肺炎患者使用序贯疗法疗效好费用低,值得临床推广。
Objective To investigate the clinical efficacy of sequential therapy for community-acquired pneumonia in the elderly and to carry out cost analysis. Methods From January 2009 to December 2011, 69 elderly patients with community acquired pneumonia diagnosed in our department were randomly divided into two groups: the control group was given ceftriaxone sodium needle 3.0 plus saline 100 ml and azithromycin 0.5 plus 5% GS250ml intravenous infusion, once / d; sequential treatment group with the same method and drug treatment for 3 ~ 4 d, until the condition improved significantly to oral cefixime tablets 0.1 g, 2 times / d , Azithromycin tablets 0.51 times / d, the total course of treatment was 10 d. The efficacy of the two groups was observed, the cost was calculated and compared. Results The clinical curative effect of both groups was good, the difference was not statistically significant (P> 0.05), but the cost of sequential treatment group was low, the difference between the two groups was statistically significant (P <0.05). Conclusion Inpatients with community-acquired pneumonia in elderly patients with sequential therapy efficacy is low cost, worthy of clinical promotion.