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中药愈口清甘油是口腔局部用药。临床上治疗牙周病、冠周炎和部分口腔溃疡均有很好的疗效。本文通过动物实验证实中药愈口清甘油有明显抑制小鼠耳廓肿胀的作用,具有抑制急性炎反应作用。对角叉菜胶所致大鼠足趾肿胀具有明显的抑制作用,并显示一定的量效关系。它在用药后牙龈微循环灌流量明显增加,表明其具有改善微循环的作用通过微循环的改善也增强其抗炎作用的发挥。对其抗炎机理初步探讨。
The more traditional Chinese medicine Qingkou glycerin is oral topical medication. Clinical treatment of periodontal disease, pericoronitis and some oral ulcers have a good effect. In this article, animal experiments were performed to verify that Chinese herbal medicine Qingkouqing glycerol significantly inhibited the swelling of the mouse’s ear and inhibited the acute inflammatory reaction. It has a significant inhibitory effect on the toe swelling of rats induced by carrageenan and shows a certain dose-effect relationship. It significantly increased the flow of gingival microcirculation after drug administration, indicating that it has the effect of improving microcirculation. The improvement of microcirculation also enhances its anti-inflammatory effect. The preliminary discussion of its anti-inflammatory mechanism.