卵巢原发性子宫内膜间质肉瘤27例临床病理分析:形态学和生物学行为特征类似于子宫低级别子宫内膜间质肉瘤

来源 :临床与实验病理学杂志 | 被引量 : 0次 | 上传用户:iamfly2000
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原发性子宫外的子宫内膜间质肿瘤非常罕见,作者报道27例卵巢原发性子宫内膜间质肉瘤的临床病理特征。患者年龄38~76岁,平均56岁。20例为单侧卵巢病变,7例累及双侧卵巢。肿瘤直径1~20 cm,平均9.5 cm。实性区域切面呈典型的黄褐色,6例伴出血和(或)坏死,囊内常存留血性液体。镜检:肿瘤常表现的独特生长模式为小细胞弥漫性生长,小动脉散布其间。14例可见纤维瘤样结构,10例可见模糊的结节状结构,2例有席纹状结构,10例伴有玻璃样物质沉积,7例伴性索样分化,6例伴平滑肌分化,6例见泡沫细胞形成。肿瘤细胞轻度异型性,核分裂象1~17个/10 Primary uterine endometrial stromal tumors are rare, the authors report the clinical and pathological features of 27 cases of primary ovarian endometrial stromal sarcoma. Patients aged 38 to 76 years, mean 56 years. 20 cases of unilateral ovarian lesions, 7 cases involving both ovaries. Tumor diameter 1 ~ 20 cm, an average of 9.5 cm. The solid area showed a typical tan, with hemorrhage and / or necrosis in 6 cases and persistent bloody fluid in the sac. Microscopic examination: The unique growth pattern of tumors often shows the diffuse growth of small cells and the interstitial of arterioles. Fibroids were found in 14 cases, vague nodules in 10 cases, lamellar structures in 2 cases, deposition of vitreous material in 10 cases, differentiation of accessory cordlike cord in 7 cases, differentiation of smooth muscle in 6 cases, See for example foam cells. Tumor cells atypia, mitotic 1 ~ 17/10
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