脾脏是体内重要的免疫器官,也是多种免疫活性细胞集居的场所。脾细胞是细胞免疫研究中经常涉及的细胞,而对脾脏中各种细胞亚群的研究,进展较快。最近发现,脾脏的塑料粘附细胞可因某种药物的作用而获得免疫抑制活性,此种抑制活性一般不具有抗原特异性。目前,此种抑制性细胞的出现已成为免疫药理学研究的课题之一。应激反应是一种常见的生理学反应,并常常导致免疫应答能力的紊乱。本文 The spleen is an important immune organ in the body, and it is also a place where many kinds of immunocompetent cells live together. Spleen cells are frequently involved cells in the study of cellular immunity, and studies on various cell subpopulations in the spleen have progressed rapidly. It has recently been found that plastic adherent cells of the spleen can obtain immunosuppressive activity due to the action of a certain drug, and such inhibitory activity generally does not have antigen specificity. At present, the emergence of such inhibitory cells has become one of the topics of immunopharmacology research. Stress response is a common physiological reaction and often leads to disorders of immune response ability. This article