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目的探讨分析继发于淀粉样变的成人限制型心肌病(RCM)的心电学特征。方法收集2013年1月1日至2015年12月31日入住本院且诊断为继发于淀粉样变的成人RCM患者病历资料,所有患者行心电图检查,部分行24h动态心电图检查,分析心电图特征及心律失常发生情况。结果共纳入16例成人RCM患者[55.00±14.20(19~74)岁],62.5%的患者为男性(10例)。心电参数分别为PR间期(180.80±44.28)ms,QRS间期99.50(87.50,108.75)ms,QT间期395.00(378.75,455.00)ms,QTc间期(447.10±43.02)ms。68.75%的患者表现为肢体导联低电压,肢体导联最大电压为(0.45±0.21)mV。93.75%的患者胸导联R波递增不良。所有患者心电图均出现了非特异性的T波低平倒置等改变(100%)。87.50%的RCM患者可见心律失常,主要表现为房性心律失常(37.50%)、窦性心动过缓(25.00%)、非持续室性心动过速(25.00%)、一度房室传导阻滞者(12.50%)、室性早搏(12.50%)、交界性心动过速(12.50%)。结论 RCM具有较为独特的心电学特征,可为临床诊断提供一定的线索与依据。
Objective To investigate the electrocardiographic features of adult restrictive cardiomyopathy (RCM) secondary to amyloidosis. Methods The data of patients admitted to our hospital from January 1, 2013 to December 31, 2015, who were diagnosed as secondary amyloidosis, were collected. All patients underwent electrocardiogram (ECG) examination and some of them underwent 24h Holter monitoring. The electrocardiographic features And arrhythmia occurred. Results A total of 16 adult RCM patients [55.00 ± 14.20 (19-74) years] were included, and 62.5% of the patients were male (10). The parameters of ECG were PR interval (180.80 ± 44.28) ms, QRS interval 99.50 (87.50,108.75) ms, QT interval 395.00 (378.75,455.00) ms and QTc interval (447.10 ± 43.02) ms respectively. 68.75% of patients showed low limb lead voltage, limb lead maximum voltage (0.45 ± 0.21) mV. 93.75% of patients with chest wave R wave increased bad. Electrocardiogram in all patients have seen non-specific T-wave inversion inversion (100%). Arrhythmia was found in 87.50% of RCM patients, including atrial arrhythmia (37.50%), sinus bradycardia (25.00%), non-sustained ventricular tachycardia (25.00%), (12.50%), premature ventricular contractions (12.50%), borderline tachycardia (12.50%). Conclusion RCM has a unique ECG characteristics, which can provide some clues and basis for clinical diagnosis.