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由于早期发现和切除率上升,所以近年来肺癌治疗效果不断提高.但即使预后较好的I期肺癌,术后5年生存率仍在60%左右。本文研究的目的是从临床和组织学所见来了解I期肺癌病人术后预后不良的特点.作者分析了日本神户大学医学院8年(1973～1981)内I期肺癌70例手术后情况,对其中鳞癌27例(38.6%),腺癌34例(48.6%),大细胞癌7例(10%),小细胞癌2例(2.8%)进行了分析。全组22例(31.4%)在三年内死亡。作者对全组病理报告包括组织学类型、亚型、分化等级、核分裂相、血
Due to the early detection and increased resection rate, the therapeutic effect of lung cancer has been continuously improved in recent years. However, even with a better prognosis of stage I lung cancer, the postoperative 5-year survival rate is still about 60%. The purpose of this study is to understand the characteristics of poor prognosis of patients with stage I lung cancer from the perspective of clinical and histological findings. The authors analyzed the postoperative status of 70 patients with stage I lung cancer during the 8 years (1973-1981) of Kobe University School of Medicine in Japan. Of these, 27 (38.6%) were squamous cell carcinomas, 34 (48.6%) were adenocarcinomas, 7 (10%) were large cell carcinomas, and 2 (2.8%) were small cell carcinomas. Twenty-two patients (31.4%) died within three years. The author’s full set of pathology reports included histological types, subtypes, differentiation grades, mitotic facies, and blood