论文部分内容阅读
弥漫性血管内凝血(DIC)是一个复杂的病理过程,它不是一个独立的疾病,而是各种疾病的一个重要的中间病理过程。已知重症传染病最易并发DIC。炎症被列为引起DIC的首要因素,尤其是革兰氏阴性细菌感染。国内总结了190例DIC,其中感染性疾病引起的DIC占32％。从病原菌来看,Corrigan分析了并发DIC的败血症患者222例,革兰氏阴性细菌198例,占89.2％,其中脑膜炎双球菌167例,占全部致病菌的75.2％,占革兰氏阴性菌的84.3％。可见革兰氏阴性细菌感染最易并发DIC。暴发型流脑休克型(即华—佛氏综合征)及内毒索引起的Schwartzmann反应实质上为DIC。Leighton认为几乎所有菌血症休克患者皆发生DIC。山本祐夫发现血液中的内毒素含量与临床症状不平行,血液中含有高
Diffuse intravascular coagulation (DIC) is a complex pathological process, it is not an independent disease, but a variety of diseases, an important intermediate pathological process. Severe infectious diseases are known to be complicated by DIC. Inflammation is cited as a primary cause of DIC, especially Gram-negative bacterial infections. Domestic 190 cases of DIC summarized, of which infectious diseases caused by DIC accounted for 32%. From the perspective of pathogens, Corrigan analyzed 222 cases of sepsis patients with concurrent DIC, 198 cases of gram-negative bacteria, accounting for 89.2%, of which 167 cases of meningococcus, accounting for 75.2% of all pathogenic bacteria, accounting for Gram-negative 84.3% of bacteria. Gram-negative bacterial infection can be seen the most complicated with DIC. The Schwartzmann response to fulminant meningitis (ie, Warfarin syndrome) and endotoxic cord is essentially DIC. Leighton believes that DIC occurs in almost all patients with bacteremic shock. Yohji Yamamoto found that the endotoxin content in the blood and clinical symptoms are not parallel, the blood contains high