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目的:引起高原医学工作者对高原低氧所致应激性溃疡的重视。方法:对病因明确的患者,详细记录其一般情况、病史、病程、症状与体征,测定血红蛋白、出血时间、凝血时间与凝血酶原时间,进行大便潜血试验,并以纤维胃镜对食管、胃与十二指肠进行检查,同时对患者予以制酸、止血、保护胃粘膜等治疗,对其中3例并失血性休克者,加以供氧、输血并使用血管活性药物进行抗休克治疗。结果:本组病例均有确切的低氧所致应激性溃疡的临床表现,其中3例并发失血性休克。经治疗后胃镜复查证实,本组溃疡全部治愈,治愈时间为10.4±4.2天。结论:急进高原后的低氧时机体所产生的影响是多方面的,由这种因素所致的应激性溃疡为高原地区所特有的一种原发性独立性疾病。其发病机理与一般应激性溃疡者相似。幽门螺杆菌在本病的发生中不起重要作用。男性青壮年县罹患本病。引起本病的大气中氧分压一般须比引起急性高原病的大气氧分压更低。治疗较易。
Objective: To cause plateau medical workers to stress stress ulcer induced by plateau. Methods: The general conditions, history, course of disease, symptoms and signs were recorded in detail. The hemoglobin, bleeding time, clotting time and prothrombin time were recorded. The fecal occult blood test was performed. The esophagus, stomach and Duodenal examination, at the same time to patients with acid, stop bleeding, protect the gastric mucosa and other treatment, of which 3 cases of hemorrhagic shock were oxygen, blood transfusion and the use of vasoactive drugs for anti-shock treatment. Results: All the patients in this group had definite clinical manifestations of stress ulcer caused by hypoxia, of which 3 patients had hemorrhagic shock. After treatment, endoscopy confirmed that all ulcers in this group were cured, the healing time was 10.4 ± 4.2 days. CONCLUSION: The effects of body hypoxia on acute altitude are manifold, and the stress ulcer caused by this factor is a kind of primary independent disease unique to the plateau. Its pathogenesis and general stress ulcer were similar. Helicobacter pylori in the pathogenesis of this disease can not play an important role. Male young county suffering from the disease. The partial pressure of oxygen in the atmosphere that causes this disease must generally be lower than the partial pressure of oxygen in the atmosphere that causes acute altitude sickness. Treatment easier.