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本实验观察了８０只家兔在急性缺氧６、１２、２４、３６、４８、６０、７１ｈ后肺指数、血浆心钠素（ＡＮＰ）、抗利尿激素（ＡＶＰ）、醛固酮（ＡＬＤ）及尿量的变化。结果表明：在缺氧２４－７２ｈ，肺指数明显升高，尿量减少；缺氧１６ｈ，血浆ＡＮＰ明显升高；而缺氧４８和６０ｈ无ＡＮＰ升高现象。缺氧７２ｈ，血浆ＡＮＦ又明显高于缺氧前水平；血浆ＡＶＰ只在缺氧２４ｈ明显升高；血浆ＡＬＤ未见显著性变化。这些结果提示：在缺氧状态下，ＡＮＰ、ＡＶＰ的释放均与缺氧暴露的时间有关。这些激素的平衡失调可能与急性缺氧性肺水肿的发生有关。
In this study, the lung index, plasma ANP, AVP, aldosterone (ALD) and urine in 80 rabbits were measured at 6,12,24,36,48,60,71h after acute hypoxia. The amount of change. The results showed that: in hypoxia 24-72h, pulmonary index was significantly increased, urine output decreased; anoxia 16h, plasma ANP was significantly increased; and hypoxia 48 and 60h no ANP increased phenomenon. After hypoxia for 72h, plasma ANF was significantly higher than that before hypoxia; plasma AVP increased significantly only 24h after hypoxia; no significant change was found in plasma ALD. These results suggest that the release of ANP and AVP in hypoxic conditions are related to the time of hypoxic exposure. The imbalance of these hormones may be related to the occurrence of acute hypoxic pulmonary edema.