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目的探讨一过性黑矇与颈动脉粥样硬化性狭窄的关系。方法选择眼科确诊的一过性黑矇和非一过性黑矇患者各80例为调查对象,均行颈动脉彩色超声检查和血液生化检查;比较2组颈动脉硬化程度及相关危险因素的差异。结果高血压史、脂代谢异常史、IMT增厚、颈动脉粥样硬化斑块、斑块分类、颈动脉粥样硬化性狭窄、狭窄程度、狭窄部位与一过性黑矇有关联,OR具有统计学意义(P<0.05)。职业、三酰甘油(TG)、胆固醇(TC)、低密度胆固醇(LDL)、空腹血糖(FPG)、收缩压(SBP)、舒张压(DBP)水平升高及HDL水平降低与一过性黑矇有关联(P<0.05)。多因素非条件Logistic回归分析,发现TG、FPG、SBP水平升高,HDL水平降低及颈动脉粥样硬化性狭窄是一过性黑矇的危险因素,其中有重度颈动脉粥样硬化性狭窄者发生一过性黑矇的危险性比无狭窄者高(P<0.05)。结论颈动脉粥样硬化性狭窄与一过性黑矇的关系密切。
Objective To investigate the relationship between transient amaurosis and carotid atherosclerosis. Methods Eighty patients with transient amaurosis and non-transient amaurosis diagnosed by ophthalmology were enrolled in this study. The carotid color ultrasound examination and blood biochemical examination were performed. The differences of carotid arteriosclerosis and related risk factors were compared between the two groups . Results Hypertension, history of abnormal lipid metabolism, IMT thickened, carotid atherosclerotic plaque, plaque classification, carotid atherosclerotic stenosis, stenosis and stenosis were associated with transient amaurosis. OR had Statistical significance (P <0.05). Occupational triglyceride (TG), cholesterol (TC), low density cholesterol (LDL), fasting blood glucose (FPG), systolic blood pressure (SBP), diastolic blood pressure (DBP) and HDL level decreased with the transient black Mongolia related (P <0.05). Multivariate non-conditional logistic regression analysis found that elevated TG, FPG, SBP levels, decreased HDL levels and carotid atherosclerosis are risk factors for transient amaurosis, including severe carotid atherosclerosis The risk of transient amaurosis was higher than that without stenosis (P <0.05). Conclusion Carotid atherosclerosis is closely related to transient amaurosis.