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慢性肾小球肾炎(GN)发生慢性肾衰的期限很广,由1～2至30～40年。作者研究肾病型慢性 GN发生慢性肾衰的因素。观察 GN 病人43例,男24例,女19例。单纯性肾病综合征31例,合并高血压12例。发病年龄2～53(平均26.7±4.8)岁,观察2～22(平均5.9±4.8)年。都经肾穿刺活检确诊,血管系膜增生性 GN 24例,膜性 GN 7例,病灶性节段性肾小球透明变性/硬化7例,微小病变4例,系膜毛细管 GN 1例。在不同阶段都得到针对发病机理的治疗,26例曾使用免疫抑制剂和抗凝血剂。
Chronic glomerulonephritis (GN) chronic renal failure occurs in a very wide period, from 1 to 2 to 30 to 40 years. The authors study the factors that contribute to chronic renal failure in chronic kidney disease. 43 cases of GN patients observed, 24 males and 19 females. Simple nephrotic syndrome in 31 cases, with hypertension in 12 cases. The age of onset ranged from 2 to 53 (mean, 26.7 ± 4.8) years and ranged from 2 to 22 (mean, 5.9 ± 4.8) years. All of them were diagnosed by renal biopsy. Among them, 24 cases were mesangial proliferative GN, 7 membranous GN, 7 cases were focal segmental glomerular degeneration / sclerosis, 4 cases were minor lesion and 1 case was mesangial capillary GN. Therapies were targeted at different stages of the pathogenesis and 26 had used immunosuppressive agents and anticoagulants.