细菌性角膜炎是严重危害患者视力的眼部感染性疾病。不同国家或地区由于地理、气候等的不同,其致病菌和药敏谱不尽相同。了解和掌握细菌病原的分布和动态变化以及常见细菌耐药性的改变,对临床诊断与治疗均有重要指导意义。就国内外细菌性角膜炎的主要病原菌、危险因素、检出率及耐药性的变化做一综述。 Bacterial keratitis is an ocular infectious disease that severely compromises the patient’s vision. Different countries or regions due to the geographical, climate and other differences, the pathogenic bacteria and drug susceptibility spectrum vary. To understand and master the distribution and dynamic changes of bacterial pathogens and common bacterial resistance changes, clinical diagnosis and treatment are important guiding significance. The main pathogens, risk factors, detection rate and drug resistance of bacterial keratitis at home and abroad were reviewed.