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世界卫生组织科学小组鉴于滋养细胞疾病在命名、诊断标准、治疗方法等各方面的不一致,提出一些建议,大致有下列几方面。一、名称方面 1.滋养细胞疾病:包括葡萄胎、侵蚀性葡萄胎,绒毛膜癌和胎盘部位滋养细胞肿瘤。而滋养细胞肿瘤(trophoblastic tumor,不用trophoblastic neop-lasm)则包括后三种病变,不包括葡萄胎,表明葡萄胎不是肿瘤,而且侵蚀性葡萄胎也不是真正的新生物。 2.侵蚀性葡萄胎:建议不再用恶性葡萄胎、破坏性葡萄胎等名称,改为侵蚀性葡萄胎(invasivemole)。 3.绒毛膜癌:不再用绒毛膜上皮癌,一律用绒毛膜癌(gestational choriocarcinoma),虽然滋养细胞亦是上皮细胞,但为胚外组织,与胚内上皮有所不同,故不用“上皮”两字。 4.胎盘部位滋养细胞肿瘤:不再用不典型绒毛膜癌、假滋养细胞肿瘤等名称,用胎盘部位滋养细胞肿瘤(placental site trophoblastic tumor简称PSTT)。
In view of the inconsistency in terms of naming, diagnostic criteria, treatment methods and other aspects of the trophoblastic disease, the WHO scientific group put forward some suggestions on the following aspects. First, the name of 1. Trophoblastic diseases: including hydatidiform mole, invasive hydatidiform mole, choriocarcinoma and placental parts of trophoblastic tumors. The trophoblastic tumor (trophoblastic neop-lasm) includes the last three lesions, not including the hydatidiform mole, indicating that the hydatidiform mole is not a tumor and that the erosive hydatidiform mole is not a true neoplasm. 2. Erosive mole: It is recommended not to use the name of malignant mole, destructive mole, to invasive moles (invasivemole). 3. Choriocarcinoma: no longer use choriocarcinoma, all with choriocarcinoma (gestational choriocarcinoma), although trophoblast cells are epithelial cells, but for the extraembryonic tissue, and embryonic epithelium are different, so do not use "epithelial Two words. 4. Placental parts of trophoblastic tumor: no longer with atypical choriocarcinoma, pseudotrophoblastic tumor and other names, placental site trophoblastic tumor (placental site trophoblastic tumor referred to as PSTT).