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筛选45岁以上男性体检资料1455份,除外病毒性肝炎,大量饮酒史(饮酒折合乙醇量男性每周≥140克);无引起继发性脂肪肝的因素,无恶性肿瘤以及无其他进展性致命性疾病。结果:共调查1455例,检出NAFLD692例,患病率为47.50%,按照2000年第五次全国人口普查沈阳地区人口构成比进行标化后,标化患病率为14.78%。随年龄增加,NAFLD患病率下降。在脂肪肝组中,体重指数≥24、腰围≥90、高血压病、糖代谢异常、代谢综合征、血脂异常症、高尿酸血症的患病率均明显高于非脂肪肝组(P<0.001)。结论:中老年男性人群具有较高的NAFLD患病率,与多种代谢性疾病如超重或肥胖、高血压、糖代谢异常、血脂异常症等密切相关。
Screening 1455 male subjects 45 years of age with the exception of viral hepatitis, a large number of alcohol consumption (alcohol equivalent alcohol intake of men weekly ≥ 140 grams); no factors that cause secondary fatty liver disease, no malignant tumor and no other progressive fatal Sexually transmitted diseases. Results: A total of 1455 cases were examined and 692 NAFLD cases were detected. The prevalence rate was 47.50%. After normalization according to the population composition ratio in Shenyang in the fifth national census in 2000, the standardized prevalence was 14.78%. With age, the prevalence of NAFLD decreases. In fatty liver group, the prevalence of body mass index≥24, waist circumference≥90, hypertension, abnormal glucose metabolism, metabolic syndrome, dyslipidemia and hyperuricemia were significantly higher than those in non-steatosis group (P < 0.001). Conclusion: The prevalence of NAFLD in middle-aged and elderly male population is closely related to many metabolic diseases such as overweight or obesity, hypertension, abnormal glucose metabolism and dyslipidemia.