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为了解卵巢所分泌的雄激素是否亦增加尿钙量的排出。对２１例绝经前、后切除卵巢患者手术前后用放射免疫法测定雌、雄激素水平，并观察尿钙排泄的变化。结果：绝经前切除双侧卵巢１３例，术后雌二醇（Ｅ２）水平明显降低，雄激素（Ｔ）水平也略有下降，尿钙排泄明显增加。绝经后切除双侧卵巢７例，术后睾酮（１）水平明显降低，尿钙与肌酐比值（Ｃａ／Ｃｒ）显著升高。表明雌激素减少明显增加了尿钙的排出量。绝经后的卵巢仍分泌一定量的雄激素，它在妇女骨质疏松中亦同时起一定的作用。
To understand whether androgen secreted by the ovaries also increase the amount of urinary calcium excretion. The levels of estrogen and androgens were measured by radioimmunoassay before and after operation in 21 cases of premenopausal and postoperative ovariectomized patients. The urinary calcium excretion was also observed. RESULTS: Thirteen patients with bilateral ovaries were resected before menopause. The estradiol (E2) level was significantly decreased and the level of androgen (T) decreased slightly. The excretion of urinary calcium was significantly increased. Postmenopausal resection of bilateral ovaries in 7 cases, postoperative testosterone (1) levels were significantly lower, urinary calcium and creatinine ratio (Ca / Cr) was significantly increased. Shows that decreased estrogen significantly increased urinary calcium excretion. Postmenopausal ovarian secretion is still a certain amount of androgen, which also plays a role in osteoporosis in women.