“旋覆花汤”出自张仲景《金匮要略》,由旋覆花、新绛(茜草)、葱茎组成。医学文献报道方中的旋覆花提取物,具有抗炎、抗肝炎、抗肝损伤、抗肿瘤和细胞毒等作用。苦豆子是新疆地产药材。始载于《新疆中草药手册》,为豆科植物苦豆子全草及种子,属于维药范畴。当代医家已从苦豆子中科学提取生物碱,制成药品,用于肝病治疗。本研究从经方“旋覆花汤”及苦豆子基本作用及应用研究出发,结合王存芬主任医师多年临床经验总结的肝病从气、血、瘀、湿、毒论治的体会,以经方“旋覆花汤”为基础方,加入苦豆子,拟以行气、疏肝、活血、解毒之剂——旋覆花苦豆子合剂。利用现代医学技术,借助小鼠免疫性肝损伤模型,以实验室检测指标为依据,实验结果初步显示:旋覆花苦豆子合剂“、旋覆花汤”、苦豆子煎剂对动物免疫性肝损伤的治疗或预防均有一定的疗效,且组间疗效有差异。 “Inverted Flower Soup” comes from Zhang Zhongjing’s “Golden Chamber”, composed of inula, new plant (grass), and onion stems. The inulae extracts reported in the medical literature have anti-inflammatory, anti-hepatitis, anti-hepatic, anti-tumor and cytotoxic effects. Sophora alopecuroides is a real estate medicinal material in Xinjiang. It was first published in the “Xinjiang Chinese Herbal Handbook”, which is a leguminous plant of Sophora alopecuroides and its seeds, belonging to the category of Uighur medicine. Modern doctors have scientifically extracted alkaloids from bitter beans and made them into medicines for the treatment of liver diseases. This study started with the study of the basic role and application of the traditional Chinese medicine “Huantaihuatang” and the bitter bean, combined with the experiences of the liver disease summarized by Wang Cunfen’s chief clinical doctor from years of experience in the treatment of qi, blood, sputum, dampness, and toxins. Side “inverted flower soup” based on the party, adding bitter beans, intended to line Qi, liver, blood, detoxification agent - infusion of flower bitter bean mixture. Using modern medical technology, with the aid of mouse immune hepatic injury model, based on laboratory testing indicators, the experimental results initially showed that: Inulahuakudou Mixture “, Inulahuatang”, bitter bean decoction on animal immunity Treatment or prevention of hepatic injury has a certain effect, and there are differences in efficacy between groups.