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急性感染性无菌性胃肠炎是至少由两群病毒引起。已经证实,婴幼儿急性腹泻的主要原因是直径约70—nm轮状病毒,据报导,72、77年在日本Norwalk等地流行胃肠炎时,从粪便滤液中见到直径约27—nm的病毒微粒;79年在英国胃肠炎流行时,从粪便滤液中也见到类似的病毒微粒,由所得到的流行病学数据提示了直径约27—nm病毒是引起家庭或集体中较大儿童和成人流行急性胃肠炎的主要原因。但要用免疫电镜(IEM)对流行性胃肠炎进行大规模的流行病学调查是不可能的,作者用一种高度敏感的放射免疫测定法(RIA)阻滞试验来检
Acute Infectious Aseptic Gastroenteritis is caused by at least two groups of viruses. It has been shown that the major cause of acute diarrhea in infants and young children is rotavirus of about 70-nm in diameter. It has been reported that in 72,77 years of age when gastroenteritis is endemic in Norwalk, Japan, about 27-nm diameter Virus particles; similar virus particles were seen from the faecal filtrate at the time of the British gastroenteritis epidemic in 1979. The epidemiological data obtained suggest that about 27-nm diameter virus is caused by larger children in families or groups And adult prevalence of acute gastroenteritis the main reason. However, large-scale epidemiological investigations of epidemic gastroenteritis using immunoelectron microscopy (IEM) are not possible and the authors use a highly sensitive radioimmunoassay (RIA) block test