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目的观察伴有焦虑、抑郁症状的稳定性心绞痛患者加用文拉法辛干预后的疗效。方法 98例稳定性心绞痛的患者,用汉密尔顿焦虑评定量表(HAMA)和汉密尔顿抑郁评定量表(HAMD)测评患者心理障碍的发生情况,将患者分为文拉法辛治疗组及对照组,治疗组在常规心绞痛治疗基础上加用文拉法辛,治疗4周后再检测上述指标,同时观察治疗前后患者心绞痛的改善情况。结果 49例治疗组患者心绞痛的改善及汉密尔顿焦虑/抑郁评定量表的评分改善明显优于对照组。结论文拉法辛使患者的焦虑及抑郁症状很快得到改善,并改善了冠心病稳定性心绞痛的疗效。
Objective To observe the effect of intervention with venlafaxine in patients with angina pectoris and anxiety associated with anxiety and depression. Methods A total of 98 patients with stable angina pectoris were enrolled in this study. Patients were divided into venlafaxine treatment group and control group with Hamilton HAMA and HAMD. Venlafaxine plus venlafaxine was given on the basis of routine angina pectoris. After 4 weeks of treatment, the above indexes were detected again, and the improvement of angina pectoris before and after treatment was observed. Results The improvement of angina pectoris and improvement of Hamilton anxiety / depression rating scale in 49 treatment groups were significantly better than those in control group. Conclusions Venlafaxine improves the symptoms of anxiety and depression in patients quickly and improves the efficacy of stable angina pectoris.