手足口病是由多种肠道病毒引起的常见传染病,以5岁以下婴幼儿发病为主,全年均可发病[1]。主要表现为口腔黏膜溃疡性疱疹及四肢末端水疱样皮疹,主要病原体为肠道病毒71型(EV71)和柯萨奇病毒A组16型(CoxA16)[2]。2008年卫生部将此病纳入法定的丙类传染病并进行网络直报。吐鲁番市位于新疆东部的吐鲁番盆地,主要以维吾尔族为主。2009年以来,吐鲁番市手足口病的发病率呈现逐年的上升趋势,且居于法定报告传染病 Hand-foot-mouth disease is a common infectious disease caused by a variety of enteroviruses, with the majority of infants and young children under 5 years of age developing disease throughout the year [1]. Mainly manifested as oral mucosal ulcer herpes and limb-end blister-like rash, the main pathogens enterovirus 71 (EV71) and Coxsackie A group 16 (CoxA16) [2]. In 2008, the Ministry of Health incorporated the disease into the legal category C infectious diseases and conducted direct online reporting. Turpan City is located in the Turpan Basin in eastern Xinjiang, mainly Uygur. Since 2009, the incidence of hand-foot-mouth disease in Turpan has been increasing year by year, and living in statutory communicable diseases