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目的探讨老年急性白血病患者医院感染的临床特点。方法对我院3年间32例老年急性白血病患者医院感染发生率、感染部位、致病菌和易感因素等进行回顾性分析。结果老年白血病患者发生医院感染率为78.1%,感染部位以口腔和呼吸系统多见;致病菌以革兰阴性杆菌为主;骨髓抑制、粒细胞缺乏者感染率明显增高。结论老年急性白血病患者医院感染发生率高,骨髓抑制、粒细胞缺乏为主要易感因素,治疗应及时应用有效抗生素,加强支持治疗。
Objective To investigate the clinical characteristics of nosocomial infection in elderly patients with acute leukemia. Methods The incidence of nosocomial infection, infection site, pathogenic bacteria and susceptibility factors in 32 elderly patients with acute leukemia in our hospital during 3 years were analyzed retrospectively. Results The incidence of nosocomial infection in elderly patients with leukemia was 78.1%. The infection sites were more common in the oral cavity and respiratory system. The pathogens were gram-negative bacilli. The infection rate of myelosuppression and agranulocytosis was significantly higher. Conclusions The incidence of nosocomial infections in elderly patients with acute leukemia is high. Myelosuppression and agranulocytosis are the main susceptible factors. Effective antibiotics should be used in the treatment and the supportive treatment should be strengthened.