论文部分内容阅读
内分泌器官的自身免疫病和系统性红斑狼疮(SLE) 等系统性自身免疫病相比,前者是器官特异性相对较强的继发性引起激素分泌功能障碍的一组特殊性疾病。免疫活性细胞之间的自身遏制和以激素为中心的对自身免疫的建立的调节机构已被广泛重视。自身免疫病实际是这些因子间的生理性平衡破坏的结果。因此内分泌器官的自身免疫病即成为研究激素和免疫系统的相互作用的重要疾病群。
Compared with systemic autoimmune diseases such as SLE, the former is a group of specific diseases with relatively strong organ-specific secondary hormonal dysfunction. Regulatory mechanisms between immunocompetent cells and hormonal-centered autoimmunity have been widely recognized. Autoimmune disease is actually the result of the physiological balance between these factors. Therefore, the autoimmune disease of endocrine organs becomes an important group of diseases for studying the interaction between hormones and immune system.