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从３４２名上海地区患者的外阴、阴道和宫颈的病变部，采集４８７份活检标本。５种病理诊断类型，经斑点杂交法检测，ＨＰＶ６、１１ＤＮＡ总阳性率：尖锐湿疣８５％、乳头瘤样增生１０．１０％、慢性宫颈炎７．１４％、鳞状上皮增生５％、生殖器正常粘膜２．６５％。５１例尖锐湿疣和１０例乳头瘤样增生，ＨＰＶ６、１１和６＋１１感染阳性率分别为：１５．６９％、２５．４９％、５８．８２％和２０％、３０％、５０％。Ｓｏｕｔｈｅｒｎ印迹转移杂交与斑点杂交的符合率，在尖锐湿疣中，ＨＰＶ６、１１和６＋１１分别为７５％、９２．３％、８６．７％；在乳头瘤样增生中，分别为１００％、３３．３％、６０％。ＡＢＣ法检测阳性率仅为６１．６７％和０％。本调查结果证实，上海地区女性尖锐湿疣和乳头瘤样增生与ＨＰＶ６、１１型感染密切相关，且以ＨＰＶ两种型别（ＨＰＶ６＋１１）混合感染为主。
487 biopsy specimens were collected from the lesions of the vulva, vagina and cervix of 342 Shanghai patients. Five types of pathological diagnosis by dot blot hybridization, HPV6, 11 DNA total positive rate: condyloma acuminatum 85%, papilloma hyperplasia 10.10%, chronic cervicitis 7.14%, 5% squamous hyperplasia, genital normal Mucosal 2.65%. In 51 cases of condyloma acuminatum and 10 cases of papillomatous hyperplasia, the positive rates of HPV6, 11 and 6 + 11 infection were 15.69%, 25.49%, 58.82% and 20%, 30% and 50% respectively. In the condyloma acuminatum, HPV6, 11 and 6 + 11 were 75%, 92.3% and 86.7% respectively, while in papilloma hyperplasia they were 100% and 33 respectively. 3%, 60%. The ABC positive rate was only 61.67% and 0%. The results of the survey confirmed that condyloma acuminata and papilloma-like hyperplasia in women in Shanghai are closely related to HPV type 6 and type 11 infection, and HPV type 2 (HPV6 + 11) is the predominant infection.