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甲苯是有机合成的重要原料,近年来又逐步的取代苯作为树脂、橡胶、沥青和醋酸纤维的溶剂,以及作为油漆和油墨的稀释剂.由于它用途广,接触甲苯的人也多.美国国家职业安全研究所(NIOSH)估计约有10万人接触甲苯。因此近年来对甲苯毒性的研究有了较多的进展。一.甲苯与其他化学物代谢的相互关系根据近年来一些学者的研究,甲苯能改变其他溶剂的代谢。池田在大鼠中观察到甲苯能抑制苯和苯乙烯的生物转化,以后他又观察到甲苯和三氯乙烯有相互抑制作用.铃木发现甲苯和正巳烷不改变
Toluene is an important raw material for organic synthesis. In recent years, benzene has been gradually replaced by benzene as a solvent for resins, rubber, asphalt and acetate, and as a diluent for paints and inks. Due to its wide range of uses, toluene is also widely used in the United States The Occupational Safety Institute (NIOSH) estimates that about 100,000 people are exposed to toluene. Therefore, in recent years, the toxicity of toluene has made more progress. Toluene and other chemical metabolism of the relationship between According to some scholars in recent years, toluene can change the metabolism of other solvents. Ikeda observed in rats that toluene inhibited the biotransformation of benzene and styrene, and later he observed the mutual inhibition of toluene and trichlorethylene Suzuki found toluene and n-hexane did not change