多器官功能衰竭(MOF)是一临床综合症,指在严重创伤、休克、烧伤、侵袭性感染如败血症和/或破坏性较大的手术24小时后,有两个以上器官发生功能衰竭。自从 Tilney 在1973年,Baue 在1975年先后提出 MOF 的概念后,临床发现MOF 的发病率并不低,在外科急症手术后为7～22%,在腹腔内严重感染中为30～50%,病死率因所累及的器官多少不一,而波动在30～100%之间,累及器官越多 Multiple organ failure (MOF) is a clinical syndrome that refers to the failure of two or more organs to develop failure after severe trauma, shock, burns, aggressive infections such as sepsis and / or more destructive surgery 24 hours after surgery. Since Tilney introduced the concept of MOF in 1973 after introducing the concept of MOF in 1973, Tilney found that the incidence of MOF was not low in clinical practice, ranging from 7 to 22% after surgical emergency surgery and from 30 to 50% in severe intra-abdominal infections. Mortality due to the number of different organs involved, and fluctuations in between 30 to 100%, involving more organs