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目的正确评估肺癌痰脱落细胞检查意义,提高痰脱落细胞病理学检查准确率,探讨肺癌早期诊断指标。方法通过31290例痰标本细胞病理学检验结果,与CT、MRI、X线、气管镜、肺穿、手术结果对照,并对传统肺癌痰脱落细胞病理学检查方法各环节进行改进。结果改良的肺癌痰脱落细胞检查阳性率由原来的22.6%提高到90.4%,达到国内外先进水平。结论痰细胞病理检查阳性率取决于痰标本正确留取,精选涂片、染色、辨认,并认为该法对诊断肺癌组织学类型是可行的,可做肺癌早期诊断方法之一。
Objective To correctly evaluate the significance of sputum exfoliated cells in lung cancer and to improve the accuracy of sputum exfoliative cytopathology examination and to explore the early diagnosis of lung cancer. Methods The results of cytopathological examination of 31290 cases of sputum specimens were compared with those of CT, MRI, X-ray, bronchoscopy, lung-penetrating and surgical procedures. The methods of pathological examination of sputum exfoliated cells in traditional lung cancer were improved. Results The positive rate of sputum exfoliated cells in lung cancer improved from 22.6% to 90.4%, reaching the advanced level at home and abroad. Conclusions The positive rate of sputum cytology depends on the correct collection of sputum samples, selective smear, staining and identification. It is feasible to diagnose the histological types of lung cancer and can be used as one of the early diagnosis methods of lung cancer.