目的　试图寻找提高对内耳脱水效应的方法。方法　分别采用丹参与甘油合用和单用甘油作正常豚鼠静脉注射 ,进行内耳膜迷路形态学观察、耳蜗微循环和外淋巴Na+、K+、Ca2 +浓度的测定。结果　发现丹参与甘油合用较单用甘油引起的内耳前庭膜及基底膜形态学变化、耳蜗微循环增加及外淋巴Na+、K+、Ca2 +浓度的变化有明显差异。结论　丹参与甘油合用明显增强了甘油经正常豚鼠前庭膜和基底膜对内淋巴的脱水作用。 Objective To find ways to improve the dehydration effect on the inner ear. Methods Dan was involved in glycerol combination and glycerol alone was used as normal guinea pig intravenously. Morphological observation of inner ear labyrinth, cochlear microcirculation and Na+, K+ and Ca2 + concentration in perilymph were measured. Results It was found that the morphological changes of the vestibular membrane and basement membrane, the increase of the microcirculation of the cochlea, and the changes of Na+, K+, and Ca2+ concentrations in the perilymph were significantly different from those of the glycerine alone. Conclusion Dan participated in the combination of glycerol significantly enhanced the dehydration effect of glycerol on the vestibular and basement membrane of normal guinea pigs.