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目的比较贲门不同位点幽门螺杆菌 (H.pylori)感染的差异；研究 H.pylori感染与贲门癌之间的关系。方法对我国食管癌高发区河北省涉县偏店、固新两乡 201例当地居民进行上消化道内镜普查，在贲门区不同位点 (内镜下 90、 120、 30和 60点位 )取活检，活检组织经 HE染色进行病理诊断， Giemsa染色找 H.pylori。结果河北省涉县居民 H.pylori感染率 61.2％；在 H.pylori感染者中，内镜下 120点位 H.pylori人群感染率为 56.7％，对侧 60点位 H.pylori人群感染率 35.8％， P< 0.05。检出贲门癌 11例，其中 9例发生在 120点位， 1例发生在 90点位。 1例发生在 60点位。结论贲门粘膜 H.pylori感染的差异与贲门癌发生有相关性。
Objective To compare the differences of Helicobacter pylori (H.pylori) infection at different sites in the cardia; to study the relationship between H.pylori infection and cardiac cancer. METHODS: A total of 201 local residents in the two townships of Shidian and Guxin of Hebei Province, a high incidence area for esophageal cancer in China, were screened for endoscopy of the upper digestive tract, and they were examined at different sites in Qimen District (90, 120, 30, and 60 points under endoscopy). Take a biopsy, biopsy tissue by HE staining for pathological diagnosis, Giemsa staining to find H.pylori. Results The H.pylori infection rate was 61.2% in She County, Hebei Province. Among the H.pylori infections, the H.pylori infection rate was 56.7% in the endoscopic 120-point H.pylori population and 35.8 in the opposite 60-point H.pylori population. %, P< 0.05. There were 11 cases of cardiac cancer detected, of which 9 cases occurred at 120 points and 1 case occurred at 90 points. One case occurred at 60 points. Conclusion The difference of H.pylori infection in cardiac mucosa is related to the occurrence of cardiac cancer.