论文部分内容阅读
对实验性失血性休克的４０只大鼠和１５只家兔静注不同剂量的抗栓酶，用激光多普勒微循环血流计测定肾表面固定部位的微循环血流量，发现用药后血流量显著增加且与尿量相一致；阻断６０只沙鼠颈动脉造成脑缺血模型，在颅顶开窗用微循环显微镜观察用药后软脑膜微循环的变化，发现微循环血流速度加快并显示一定的冲击力，且能减少白细胞数及贴壁滚动；用２０只家兔做成ＤＩＣ模型，给抗栓酶后观察肠系膜微循环，发现毛细血管开放数增多，微循环流态改善。观察３３例脑血栓形成期病人用抗栓酶治疗前后甲襞微循环的变化，发现治疗后微循环总积分值改善，流态改善更明显
40 hemorrhagic shock rats and 15 rabbits intravenous injection of different doses of antithrombin, laser Doppler microcirculation flowmeter determination of the fixed surface of the renal microcirculatory blood flow and found that after the application of blood Flow significantly increased and consistent with the volume of urine; block 60 carotid artery occlusion caused by cerebral ischemia model in the skull window using a microcirculation microscope to observe changes in the pia mater microcirculation and found that microcirculation blood flow accelerated And showed a certain impact, and can reduce the number of white blood cells and adherent rolling; DIC model made with 20 rabbits to observe the mesenteric microcirculation after antithrombotic enzyme, found that the number of open capillaries increased microcirculation flow pattern improved. To observe the changes of nailfold microcirculation before and after treatment with antithrombin in 33 patients with cerebral thrombosis, and found that the total score of microcirculation improved and the fluid flow improved more obviously