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目的探究新生儿重症监护室(NICU)婴儿悬浮红细胞(SRBC)输注次数的影响因素,为NICU婴儿科学合理输血提供依据,从而降低输血风险。方法收集2015年1月-12月期间,NICU进行过SRBC输注治疗的婴儿病历资料,采用卡方检验分析其临床特点与SRBC输注次数的关系,多因素Logistic回归分析进行统计学分析。结果SRBC输注次数不同的3组婴儿日龄、胎龄、出生体重、住院时间、是否感染、孕母是否有妊娠合并症分布,差异均有统计学意义(P值均<0.05);多因素logistic回归分析结果显示日龄、出生体重、住院时间、感染、孕母有妊娠合并症均显著影响SRBC输注次数,其中日龄、出生体重是保护因素(OR分别为0.951、0.962,P值均<0.05),住院时间长、感染、孕母有妊娠合并症是独立危险因素(OR分别为1.097、1.946、2.653,P值均<0.05),胎龄不是影响SRBC输注次数的显著因素(P>0.05)。结论日龄、出生体重是NICU婴儿输注SRBC的保护因素,住院时间、感染、孕母妊娠合并症是NICU婴儿SRBC输注次数的危险因素;应该通过科学的临床治疗措施增加保护因素,减少危险因素,以减少婴儿SRBC输注次数,降低输血风险。
Objective To investigate the influencing factors of infant infantile red blood cell (SRBC) infusions in neonatal intensive care unit (NICU), and to provide basis for scientific and rational blood transfusion in NICU infants, so as to reduce the risk of blood transfusion. Methods The data of infant medical records collected by NICU from January 2015 to December 2015 in NICU were collected. The relationship between the clinical features and the number of infusions of SRBC was analyzed by chi-square test. Multivariate logistic regression analysis was used to analyze the data. Results There were statistically significant differences in the distribution of gestational complications in pregnant women among three groups of infants with different numbers of SRBC infants (P <0.05). There were no significant differences in the age, gestational age, birth weight, hospital stay, The results of logistic regression analysis showed that the number of SRBC infusion significantly influenced the number of SRBC infants, including age, birth weight, length of hospital stay, infection and gestational complications in pregnant women. The age and birth weight were protective factors (OR = 0.951,0.962, P = (OR = 1.097, 1.946, 2.653, P <0.05 respectively). The gestational age was not a significant factor influencing the times of SRBC infusion (P <0.05), and the length of hospital stay, infection and pregnancy complications were independent risk factors > 0.05). Conclusions Age, birth weight are the protective factors of NICU infants in infusing SRBC, hospital stay, infection and pregnancy complication are the risk factors for NICU infants’ number of SRBC infants. The protective factors should be increased by scientific clinical treatment to reduce the risk Factors to reduce the number of infant SRBC transfusions, reducing the risk of blood transfusion.