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作者用心得安治疗严重的周期性偏头痛30例,平均每周发作1.8次,用其它方法无效。头4周不用任何药物,然后分成心得安组和对照组,心得安剂量为120毫克/日,3个月为一疗程,共治疗2个疗程。结果表明,心得安治疗期偏头痛发作次数明显减少,9例发作次数减少50％以上,其中5例减少100％;9例减少50％以下,其余12例症状无好转或加重。据推测,心得安在偏头痛初期可抑制脑皮质表面的小动脉痉挛;在偏头痛发作期可抑制反应性血管扩张;此外,心得安的膜稳定作用及其所引起的局部麻醉作用也很重要。作者认为心得安是预防周期性偏头
The author used Enron to treat severe cyclical migraine in 30 cases, with an average of 1.8 episodes per week, with other methods ineffective. The first 4 weeks without any drugs, and then divided into experience group and control group, propranolol dose 120 mg / day, 3 months for a course of treatment, a total of 2 courses of treatment. The results showed that the number of episodes of propranolol treatment significantly reduced the number of migraine attacks, the number of attacks in 9 cases decreased by more than 50%, of which 5 cases decreased by 100%; 9 cases decreased by 50% or less, the remaining 12 cases without improvement or worsening of symptoms. Presumably, propranolol suppresses arteriolar spasms on the surface of the cerebral cortex in the early stages of migraine, inhibits reactive vasodilation in migraine attacks, and diastasy of membrane stabilization and local anesthetic effects are also important . The author believes empathy is a preventive cyclical migraine