Dear Editor,rnRecently we read several articles related to sperm morphology [1-3] published on the Special Issue of Asian Journal of Andrology on Semen Analysis in 21st Century Medicine and were quite enlightened; herein we would like to present some of our views and suggestions.rnAssessment of sperm morphology, motility and concentration provides a basis for decision on patient care. A number of studies have shown a statistical association between morphologically normal spermatozoa and fertility [4, 5]. Data from assisted reproductive technology programs also suggest that, if the percentage of sperm with normal morphology falls below 15%assessed with methods and definitions described in the Manual, the fertilization rate in vitro decreases [6].