肠球菌是引起临床感染的常见病原菌之一，固有多种抗生素抗性，临床上常采用协同用药治疗肠球菌感染，例如采用青霉素、氨于青霉素或万古霉素与氨基糖贰类药物联合使用，但是当肠球菌获得了氨基糖式类活性酶后，会发展成高度氨基糖忒类耐药性（MIC，≥2000μg／ml）．而失去协 Enterococcus is one of the common pathogens that cause clinical infection. It is inherently resistant to many antibiotics. It is commonly used clinically to treat enterococcal infections such as penicillin, ammonia in penicillin or vancomycin in combination with aminoglycosides, However, enterococci develop aminoglycoside-like enzymes that develop into highly aminoglycoside resistance (MIC, ≥2000 μg / ml). And lost association